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Eduardo Marbán Selected Research

MCC 134

3/2003MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning.

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Eduardo Marbán Research Topics

Disease

48Myocardial Infarction
06/2021 - 03/2003
21Infarction (Infarctions)
01/2020 - 02/2006
20Heart Failure
12/2021 - 01/2002
13Cicatrix (Scar)
01/2021 - 10/2007
12Cardiomyopathies (Cardiomyopathy)
01/2022 - 11/2004
9Heart Diseases (Heart Disease)
01/2020 - 08/2004
8Ventricular Tachycardia
01/2022 - 07/2005
8Inflammation (Inflammations)
12/2021 - 03/2015
7Fibrosis (Cirrhosis)
12/2021 - 01/2014
7Hypertrophy
06/2021 - 07/2007
7Ischemia
08/2015 - 02/2002
6Cardiac Sudden Death (Sudden Cardiac Arrest)
11/2017 - 07/2005
6Cardiac Arrhythmias (Arrythmia)
06/2014 - 01/2002
5Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker)
12/2022 - 01/2018
5Ventricular Remodeling
11/2021 - 01/2011
5Cardiovascular Diseases (Cardiovascular Disease)
01/2020 - 07/2007
5Left Ventricular Dysfunction
01/2020 - 04/2007
3COVID-19
12/2020 - 01/2020
3Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2020 - 03/2015
3Cardiomegaly (Heart Hypertrophy)
01/2018 - 07/2007
3Myocardial Ischemia (Ischemic Heart Diseases)
10/2014 - 11/2003
2Neoplasms (Cancer)
01/2022 - 11/2017
2Myocarditis (Carditis)
11/2021 - 01/2020
2Infections
12/2020 - 08/2012
2Sudden Death
01/2020 - 01/2002
2Ventricular Fibrillation
01/2020 - 03/2012
2Hypertension (High Blood Pressure)
01/2018 - 01/2016
2Hemorrhage
11/2016 - 06/2010
2Heart Block
12/2014 - 08/2012
2Ventricular Dysfunction
02/2014 - 12/2013
2Reperfusion Injury
01/2012 - 02/2002
2Aneuploidy (Aneuploid)
01/2011 - 07/2010
2Chromosome Aberrations (Chromosome Abnormalities)
01/2011 - 07/2010
2Hypotension (Low Blood Pressure)
08/2004 - 09/2002
1Hypersensitivity (Allergy)
12/2022
1Neoplasm Metastasis (Metastasis)
01/2022
1Graft vs Host Disease (Graft-Versus-Host Disease)
11/2021
1Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
06/2021
1Immune System Diseases (Immune Disorders)
06/2021
1Muscular Dystrophies (Muscular Dystrophy)
01/2021
1Critical Illness (Critically Ill)
12/2020
1Severe Acute Respiratory Syndrome
12/2020
1Cytokine Release Syndrome
01/2020
1No-Reflow Phenomenon
10/2019
1Atrioventricular Block
01/2019
1Atrial Remodeling
10/2018
1Muscular Diseases (Myopathy)
01/2018
1Stroke (Strokes)
01/2018
1Cerebral Hemorrhage
01/2018
1Fibrosarcoma
11/2017
1Pulmonary Hypertension
01/2017

Drug/Important Bio-Agent (IBA)

39chenodeoxycholate sulfate conjugate (CDCS)IBA
12/2022 - 02/2007
8Proteins (Proteins, Gene)FDA Link
01/2022 - 11/2004
6GadoliniumIBA
11/2017 - 06/2008
4CalciumIBA
11/2020 - 10/2002
4Biomarkers (Surrogate Marker)IBA
01/2020 - 03/2012
4CollagenIBA
01/2017 - 03/2013
4Adenosine Triphosphate (ATP)IBA
02/2006 - 02/2002
3Biological ProductsIBA
01/2022 - 06/2008
3PotassiumIBA
11/2017 - 11/2003
3salicylhydroxamic acid (SHAM)IBA
01/2017 - 01/2014
3IronIBA
11/2016 - 05/2010
3Allopurinol (Remid)FDA LinkGeneric
02/2006 - 02/2002
3mitochondrial K(ATP) channelIBA
08/2004 - 09/2002
2Interleukin-10 (Interleukin 10)IBA
11/2021 - 01/2018
2Untranslated RNA (Noncoding RNA)IBA
06/2021 - 01/2018
2RNA (Ribonucleic Acid)IBA
06/2021 - 01/2018
2CateninsIBA
01/2020 - 03/2015
2DystrophinIBA
01/2019 - 01/2018
2SaltsIBA
11/2017 - 01/2016
2Ion Channels (Ion Channel)IBA
03/2015 - 01/2002
2Contrast MediaIBA
09/2014 - 05/2014
2Oxygen (Dioxygen)IBA
01/2011 - 07/2010
2AntioxidantsIBA
07/2010 - 02/2002
2Xanthine OxidaseIBA
02/2006 - 11/2004
2Oxypurinol (Oxipurinol)IBA
02/2006 - 09/2003
2Oxidants (Oxidizing Agents)IBA
11/2004 - 10/2003
2Diazoxide (Hyperstat)FDA Link
03/2003 - 09/2002
1Mitogen-Activated Protein KinasesIBA
01/2022
1Troponin IIBA
06/2021
1Caseins (Casein)FDA Link
01/2021
1Connexin 43 (Connexin43)IBA
01/2021
1Adrenergic Agents (Adrenergic Drugs)IBA
11/2020
1Transcription Factors (Transcription Factor)IBA
01/2019
1Angiotensin IIIBA
01/2018

Therapy/Procedure

18Therapeutics
12/2022 - 02/2006
16Cell- and Tissue-Based Therapy (Cell Therapy)
12/2022 - 01/2012
11Transplantation
01/2019 - 07/2005
4Ligation
11/2020 - 05/2011
3Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
12/2008 - 04/2007
2Intravenous Infusions
12/2022 - 12/2020
2Aftercare (After-Treatment)
01/2017 - 02/2014
2Catheters
01/2016 - 08/2012
2Thoracotomy
01/2014 - 01/2011
1Organ Transplantation
11/2021
1Immunomodulation
01/2021
1Heart-Assist Devices
01/2020
1Critical Care (Surgical Intensive Care)
01/2020
1Cell Transplantation
01/2019
1Denervation
01/2019